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Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis.

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Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes.

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PA28γ-20S proteasome is a proteolytic complex committed to degrade unfolded proteins.

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Interferon-inducible phospholipids govern IFITM3-dependent endosomal antiviral immunity.

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Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.

EMBO Mol Med 2024; 1379-1403. doi: 10.1038/s44321-024-00071-9

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FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer.

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Intercepting YAP Activation in Prostate Cancer Blocks Neuroendocrine Progression.

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Regulation of fc receptor endocytic trafficking by ubiquitination.

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Trends Immunol 2016; 790-802. doi: 10.1016/j.it.2016.08.015

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Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay.

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Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells.

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Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells.

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CD155: A Multi-Functional Molecule in Tumor Progression.

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Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells.

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CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers.

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Human skin-resident CD8+ T cells require RUNX2 and RUNX3 for induction of cytotoxicity and expression of the integrin CD49a.

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Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity.

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CCL3 is produced by aged neutrophils across cancers and promotes tumor growth.

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