Venereau E, Casalgrandi M, Schiraldi M, Antoine DJ, Cattaneo A, De Marchis F, Liu J, Antonelli A, Preti A, Raeli L, Shams SS, Yang H, Varani L, Andersson U, Tracey KJ, Bachi A, Uguccioni M, Bianchi ME

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release.

J Exp Med 2012; 1519-28. doi: 10.1084/jem.20120189

Ricciardi S, Ungaro F, Hambrock M, Rademacher N, Stefanelli G, Brambilla D, Sessa A, Magagnotti C, Bachi A, Giarda E, Verpelli C, Kilstrup-Nielsen C, Sala C, Kalscheuer VM, Broccoli V

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

Nat Cell Biol 2012; 911-23. doi: 10.1038/ncb2566

Gaetani M, Matafora V, Saare M, Spiliotopoulos D, Mollica L, Quilici G, Chignola F, Mannella V, Zucchelli C, Peterson P, Bachi A, Musco G

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome.

Nucleic Acids Res 2012; 11756-68. doi: 10.1093/nar/gks933

Lechman ER, Gentner B, van Galen P, Giustacchini A, Saini M, Boccalatte FE, Hiramatsu H, Restuccia U, Bachi A, Voisin V, Bader GD, Dick JE, Naldini L

Attenuation of miR-126 activity expands HSC in vivo without exhaustion.

Cell Stem Cell 2012; 799-811. doi: 10.1016/j.stem.2012.09.001

Drago D, Cossetti C, Iraci N, Gaude E, Musco G, Bachi A, Pluchino S

The stem cell secretome and its role in brain repair.

Biochimie 2013; 2271-85. doi: 10.1016/j.biochi.2013.06.020

Glaudemans B, Terryn S, Gölz N, Brunati M, Cattaneo A, Bachi A, Al-Qusairi L, Ziegler U, Staub O, Rampoldi L, Devuyst O

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing.

Pflugers Arch 2014; 343-56. doi: 10.1007/s00424-013-1321-1

Yam XY, Birago C, Fratini F, Di Girolamo F, Raggi C, Sargiacomo M, Bachi A, Berry L, Fall G, Currà C, Pizzi E, Breton CB, Ponzi M

Proteomic analysis of detergent-resistant membrane microdomains in trophozoite blood stage of the human malaria parasite Plasmodium falciparum.

Mol Cell Proteomics 2013; 3948-61. doi: 10.1074/mcp.M113.029272

Magagnotti C, Matassa PG, Bachi A, Vendettuoli V, Fermo I, Colnaghi MR, Carletti RM, Mercadante D, Fattore E, Mosca F, Andolfo A

Calcium signaling-related proteins are associated with broncho-pulmonary dysplasia progression.

J Proteomics 2013; 401-12. doi: 10.1016/j.jprot.2013.10.007

Zucchelli C, Tamburri S, Quilici G, Palagano E, Berardi A, Saare M, Peterson P, Bachi A, Musco G

Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1.

FEBS J 2014; 216-31. doi: 10.1111/febs.12588

Lorenzato A, Magrì A, Matafora V, Audrito V, Arcella P, Lazzari L, Montone M, Lamba S, Deaglio S, Siena S, Bertotti A, Trusolino L, Bachi A, Di Nicolantonio F, Bardelli A, Arena S

Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer.

Cancers (Basel) 2020; . doi: 10.3390/cancers12030685

Raule M, Cerruti F, Benaroudj N, Migotti R, Kikuchi J, Bachi A, Navon A, Dittmar G, Cascio P

PA28αβ reduces size and increases hydrophilicity of 20S immunoproteasome peptide products.

Chem Biol 2014; 470-480. doi: 10.1016/j.chembiol.2014.02.006

Gregorc V, Novello S, Lazzari C, Barni S, Aieta M, Mencoboni M, Grossi F, De Pas T, de Marinis F, Bearz A, Floriani I, Torri V, Bulotta A, Cattaneo A, Grigorieva J, Tsypin M, Roder J, Doglioni C, Levra MG, Petrelli F, Foti S, Viganò M, Bachi A, Roder H

Predictive value of a proteomic signature in patients with non-small-cell lung cancer treated with second-line erlotinib or chemotherapy (PROSE): a biomarker-stratified, randomised phase 3 trial.

Lancet Oncol 2014; 713-21. doi: 10.1016/S1470-2045(14)70162-7

Cazzalini O, Sommatis S, Tillhon M, Dutto I, Bachi A, Rapp A, Nardo T, Scovassi AI, Necchi D, Cardoso MC, Stivala LA, Prosperi E

CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis.

Nucleic Acids Res 2014; 8433-48. doi: 10.1093/nar/gku533

Cossetti C, Iraci N, Mercer TR, Leonardi T, Alpi E, Drago D, Alfaro-Cervello C, Saini HK, Davis MP, Schaeffer J, Vega B, Stefanini M, Zhao C, Muller W, Garcia-Verdugo JM, Mathivanan S, Bachi A, Enright AJ, Mattick JS, Pluchino S

Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells.

Mol Cell 2014; 193-204. doi: 10.1016/j.molcel.2014.08.020

Matafora V, Cuccurullo M, Beneduci A, Petrazzuolo O, Simeone A, Anastasio P, Mignani R, Feriozzi S, Pisani A, Comotti C, Bachi A, Capasso G

Early markers of Fabry disease revealed by proteomics.

Mol Biosyst 2015; 1543-51. doi: 10.1039/c4mb00707g

Jachetti E, Caputo S, Mazzoleni S, Brambillasca CS, Parigi SM, Grioni M, Piras IS, Restuccia U, Calcinotto A, Freschi M, Bachi A, Galli R, Bellone M

Tenascin-C Protects Cancer Stem-like Cells from Immune Surveillance by Arresting T-cell Activation.

Cancer Res 2015; 2095-108. doi: 10.1158/0008-5472.CAN-14-2346

Poitelon Y, Bogni S, Matafora V, Della-Flora Nunes G, Hurley E, Ghidinelli M, Katzenellenbogen BS, Taveggia C, Silvestri N, Bachi A, Sannino A, Wrabetz L, Feltri ML

Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination.

Nat Commun 2015; 8303. doi: 10.1038/ncomms9303

Matafora V, Zagato L, Ferrandi M, Molinari I, Zerbini G, Casamassima N, Lanzani C, Delli Carpini S, Trepiccione F, Manunta P, Bachi A, Capasso G

Quantitative proteomics reveals novel therapeutic and diagnostic markers in hypertension.

BBA Clin 2014; 79-87. doi: 10.1016/j.bbacli.2014.10.001

Brunati M, Perucca S, Han L, Cattaneo A, Consolato F, Andolfo A, Schaeffer C, Olinger E, Peng J, Santambrogio S, Perrier R, Li S, Bokhove M, Bachi A, Hummler E, Devuyst O, Wu Q, Jovine L, Rampoldi L

The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.

Elife 2015; e08887. doi: 10.7554/eLife.08887

Heise C, Taha E, Murru L, Ponzoni L, Cattaneo A, Guarnieri FC, Montani C, Mossa A, Vezzoli E, Ippolito G, Zapata J, Barrera I, Ryazanov AG, Cook J, Poe M, Stephen MR, Kopanitsa M, Benfante R, Rusconi F, Braida D, Francolini M, Proud CG, Valtorta F, Passafaro M, Sala M, Bachi A, Verpelli C, Rosenblum K, Sala C

eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.

Cereb Cortex 2017; 2226-2248. doi: 10.1093/cercor/bhw075

Reber S, Stettler J, Filosa G, Colombo M, Jutzi D, Lenzken SC, Schweingruber C, Bruggmann R, Bachi A, Barabino SM, Mühlemann O, Ruepp MD

Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants.

EMBO J 2016; 1504-21. doi: 10.15252/embj.201593791

Wu KZ, Wang GN, Fitzgerald J, Quachthithu H, Rainey MD, Cattaneo A, Bachi A, Santocanale C

DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach.

Nucleic Acids Res 2016; 8786-8798. doi: 10.1093/nar/gkw626

Drago D, Basso V, Gaude E, Volpe G, Peruzzotti-Jametti L, Bachi A, Musco G, Andolfo A, Frezza C, Mondino A, Pluchino S

Metabolic determinants of the immune modulatory function of neural stem cells.

J Neuroinflammation 2016; 232. doi: 10.1186/s12974-016-0667-7

Soncini M, Corna G, Moresco M, Coltella N, Restuccia U, Maggioni D, Raccosta L, Lin CY, Invernizzi F, Crocchiolo R, Doglioni C, Traversari C, Bachi A, Bernardi R, Bordignon C, Gustafsson JÅ, Russo V

24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development.

Proc Natl Acad Sci U S A 2016; E6219-E6227. doi: 10.1073/pnas.1613332113

Piccini A, Castroflorio E, Valente P, Guarnieri FC, Aprile D, Michetti C, Bramini M, Giansante G, Pinto B, Savardi A, Cesca F, Bachi A, Cattaneo A, Wren JD, Fassio A, Valtorta F, Benfenati F, Giovedì S

APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.

Cell Rep 2017; 3596-3611. doi: 10.1016/j.celrep.2017.11.073

Poitelon Y, Matafora V, Silvestri N, Zambroni D, McGarry C, Serghany N, Rush T, Vizzuso D, Court FA, Bachi A, Wrabetz L, Feltri ML

A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies.

J Neurochem 2018; 245-257. doi: 10.1111/jnc.14295

Luciani M, Di Febo T, Orsini M, Krasteva I, Cattaneo A, Podaliri Vulpiani M, Di Pancrazio C, Bachi A, Tittarelli M

Trypanosoma equiperdum Low Molecular Weight Proteins As Candidates for Specific Serological Diagnosis of Dourine.

Front Vet Sci 2018; 40. doi: 10.3389/fvets.2018.00040

Osti D, Del Bene M, Rappa G, Santos M, Matafora V, Richichi C, Faletti S, Beznoussenko GV, Mironov A, Bachi A, Fornasari L, Bongetta D, Gaetani P, DiMeco F, Lorico A, Pelicci G

Clinical Significance of Extracellular Vesicles in Plasma from Glioblastoma Patients.

Clin Cancer Res 2019; 266-276. doi: 10.1158/1078-0432.CCR-18-1941

Gaviraghi M, Vivori C, Pareja Sanchez Y, Invernizzi F, Cattaneo A, Santoliquido BM, Frenquelli M, Segalla S, Bachi A, Doglioni C, Pelechano V, Cittaro D, Tonon G

Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus.

EMBO J 2018; . doi: 10.15252/embj.201899179

Zucchelli C, Tamburri S, Filosa G, Ghitti M, Quilici G, Bachi A, Musco G

Sp140 is a multi-SUMO-1 target and its PHD finger promotes SUMOylation of the adjacent Bromodomain.

Biochim Biophys Acta Gen Subj 2019; 456-465. doi: 10.1016/j.bbagen.2018.11.011

Martano G, Borroni EM, Lopci E, Cattaneo MG, Mattioli M, Bachi A, Decimo I, Bifari F

Metabolism of Stem and Progenitor Cells: Proper Methods to Answer Specific Questions.

Front Mol Neurosci 2019; 151. doi: 10.3389/fnmol.2019.00151

Nigro EA, Distefano G, Chiaravalli M, Matafora V, Castelli M, Pesenti Gritti A, Bachi A, Boletta A

Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness.

Sci Rep 2019; 16640. doi: 10.1038/s41598-019-53061-0

Martano G, Leone M, D'Oro P, Matafora V, Cattaneo A, Masseroli M, Bachi A

SMfinder: Small Molecules Finder for Metabolomics and Lipidomics Analysis.

Anal Chem 2020; 8874-8882. doi: 10.1021/acs.analchem.0c00585

Chernorudskiy A, Varone E, Colombo SF, Fumagalli S, Cagnotto A, Cattaneo A, Briens M, Baltzinger M, Kuhn L, Bachi A, Berardi A, Salmona M, Musco G, Borgese N, Lescure A, Zito E

Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity.

Proc Natl Acad Sci U S A 2020; 21288-21298. doi: 10.1073/pnas.2003847117

Boulpicante M, Darrigrand R, Pierson A, Salgues V, Rouillon M, Gaudineau B, Khaled M, Cattaneo A, Bachi A, Cascio P, Apcher S

Tumors escape immunosurveillance by overexpressing the proteasome activator PSME3.

Oncoimmunology 2020; 1761205. doi: 10.1080/2162402X.2020.1761205

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