Del Sal G, Manfioletti G, Gustincich S, Ruaro E, Schneider C

New lambda and plasmid vectors for expression cloning in mammalian cells.

Biotechniques 1994; 134-8.

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Zanetti M, Del Sal G, Storici P, Schneider C, Romeo D

The cDNA of the neutrophil antibiotic Bac5 predicts a pro-sequence homologous to a cysteine proteinase inhibitor that is common to other neutrophil antibiotics.

J Biol Chem 1993; 522-6.

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Del Sal G, Ruaro EM, Utrera R, Cole CN, Levine AJ, Schneider C

Gas1-induced growth suppression requires a transactivation-independent p53 function.

Mol Cell Biol 1995; 7152-60. doi: 10.1128/MCB.15.12.7152

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Del Sal G, Murphy M, Ruaro E, Lazarevic D, Levine AJ, Schneider C

Cyclin D1 and p21/waf1 are both involved in p53 growth suppression.

Oncogene 1996; 177-85.

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DelSal G, Loda M, Pagano M

Cell cycle and cancer: critical events at the G1 restriction point.

Crit Rev Oncog 1996; 127-42. doi: 10.1615/critrevoncog.v7.i1-2.80

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Ruaro EM, Collavin L, Del Sal G, Haffner R, Oren M, Levine AJ, Schneider C

A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1.

Proc Natl Acad Sci U S A 1997; 4675-80. doi: 10.1073/pnas.94.9.4675

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Saccone S, Sandy P, Meroni G, Gostissa M, Della Valle G, Del Sal G

Assignment of the E1A-regulated transcription factor E4F gene (E4F1) to human chromosome band 16p13.3 by in situ hybridization and somatic cell hybrids.

Cytogenet Cell Genet 1998; 99-100. doi: 10.1159/000015075

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Gostissa M, Hengstermann A, Fogal V, Sandy P, Schwarz SE, Scheffner M, Del Sal G

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

EMBO J 1999; 6462-71. doi: 10.1093/emboj/18.22.6462

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Sandy P, Gostissa M, Fogal V, Cecco LD, Szalay K, Rooney RJ, Schneider C, Del Sal G

p53 is involved in the p120E4F-mediated growth arrest.

Oncogene 2000; 188-99. doi: 10.1038/sj.onc.1203250

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Stebel M, Vatta P, Ruaro ME, Del Sal G, Parton RG, Schneider C

The growth suppressing gas1 product is a GPI-linked protein.

FEBS Lett 2000; 152-8. doi: 10.1016/s0014-5793(00)02004-4

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Fogal V, Gostissa M, Sandy P, Zacchi P, Sternsdorf T, Jensen K, Pandolfi PP, Will H, Schneider C, Del Sal G

Regulation of p53 activity in nuclear bodies by a specific PML isoform.

EMBO J 2000; 6185-95. doi: 10.1093/emboj/19.22.6185

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Benetti R, Del Sal G, Monte M, Paroni G, Brancolini C, Schneider C

The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.

EMBO J 2001; 2702-14. doi: 10.1093/emboj/20.11.2702

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D'Orazi G, Cecchinelli B, Bruno T, Manni I, Higashimoto Y, Saito S, Gostissa M, Coen S, Marchetti A, Del Sal G, Piaggio G, Fanciulli M, Appella E, Soddu S

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

Nat Cell Biol 2002; 11-9. doi: 10.1038/ncb714

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Strano S, Fontemaggi G, Costanzo A, Rizzo MG, Monti O, Baccarini A, Del Sal G, Levrero M, Sacchi A, Oren M, Blandino G

Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

J Biol Chem 2002; 18817-26. doi: 10.1074/jbc.M201405200

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Zacchi P, Gostissa M, Uchida T, Salvagno C, Avolio F, Volinia S, Ronai Z, Blandino G, Schneider C, Del Sal G

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults.

Nature 2002; 853-7. doi: 10.1038/nature01120

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Dahle Ø, Andersen TØ, Nordgård O, Matre V, Del Sal G, Gabrielsen OS

Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner.

Eur J Biochem 2003; 1338-48. doi: 10.1046/j.1432-1033.2003.03504.x

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Monte M, Benetti R, Buscemi G, Sandy P, Del Sal G, Schneider C

The cell cycle-regulated protein human GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function.

J Biol Chem 2003; 30356-64. doi: 10.1074/jbc.M302902200

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Gostissa M, Hofmann TG, Will H, Del Sal G

Regulation of p53 functions: let's meet at the nuclear bodies.

Curr Opin Cell Biol 2003; 351-7. doi: 10.1016/s0955-0674(03)00038-3

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Tessari MA, Gostissa M, Altamura S, Sgarra R, Rustighi A, Salvagno C, Caretti G, Imbriano C, Mantovani R, Del Sal G, Giancotti V, Manfioletti G

Transcriptional activation of the cyclin A gene by the architectural transcription factor HMGA2.

Mol Cell Biol 2003; 9104-16. doi: 10.1128/MCB.23.24.9104-9116.2003

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Tullo A, Mastropasqua G, Bourdon JC, Centonze P, Gostissa M, Costanzo A, Levrero M, Del Sal G, Saccone C, Sbisà E

Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target.

Oncogene 2003; 8738-48. doi: 10.1038/sj.onc.1206967

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Monte M, Benetti R, Collavin L, Marchionni L, Del Sal G, Schneider C

hGTSE-1 expression stimulates cytoplasmic localization of p53.

J Biol Chem 2004; 11744-52. doi: 10.1074/jbc.M311123200

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Paroni G, Mizzau M, Henderson C, Del Sal G, Schneider C, Brancolini C

Caspase-dependent regulation of histone deacetylase 4 nuclear-cytoplasmic shuttling promotes apoptosis.

Mol Biol Cell 2004; 2804-18. doi: 10.1091/mbc.e03-08-0624

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Collavin L, Gostissa M, Avolio F, Secco P, Ronchi A, Santoro C, Del Sal G

Modification of the erythroid transcription factor GATA-1 by SUMO-1.

Proc Natl Acad Sci U S A 2004; 8870-5. doi: 10.1073/pnas.0308605101

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Mantovani F, Piazza S, Gostissa M, Strano S, Zacchi P, Mantovani R, Blandino G, Del Sal G

Pin1 links the activities of c-Abl and p300 in regulating p73 function.

Mol Cell 2004; 625-36. doi: 10.1016/j.molcel.2004.05.007

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Mantovani F, Gostissa M, Collavin L, Del Sal G

KeePin' the p53 family in good shape.

Cell Cycle 2004; 905-11.

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Gostissa M, Morelli M, Mantovani F, Guida E, Piazza S, Collavin L, Brancolini C, Schneider C, Del Sal G

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

J Biol Chem 2004; 48013-23. doi: 10.1074/jbc.M310801200

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Imbriano C, Gurtner A, Cocchiarella F, Di Agostino S, Basile V, Gostissa M, Dobbelstein M, Del Sal G, Piaggio G, Mantovani R

Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

Mol Cell Biol 2005; 3737-51. doi: 10.1128/MCB.25.9.3737-3751.2005

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Strano S, Monti O, Pediconi N, Baccarini A, Fontemaggi G, Lapi E, Mantovani F, Damalas A, Citro G, Sacchi A, Del Sal G, Levrero M, Blandino G

The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

Mol Cell 2005; 447-59. doi: 10.1016/j.molcel.2005.04.008

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Berger M, Stahl N, Del Sal G, Haupt Y

Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage.

Mol Cell Biol 2005; 5380-8. doi: 10.1128/MCB.25.13.5380-5388.2005

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Gueven N, Becherel OJ, Birrell G, Chen P, DelSal G, Carney JP, Grattan-Smith P, Lavin MF

Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype.

Cancer Res 2006; 2907-12. doi: 10.1158/0008-5472.CAN-05-3428

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Frasca F, Rustighi A, Malaguarnera R, Altamura S, Vigneri P, Del Sal G, Giancotti V, Pezzino V, Vigneri R, Manfioletti G

HMGA1 inhibits the function of p53 family members in thyroid cancer cells.

Cancer Res 2006; 2980-9. doi: 10.1158/0008-5472.CAN-05-2637

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Braithwaite AW, Del Sal G, Lu X

Some p53-binding proteins that can function as arbiters of life and death.

Cell Death Differ 2006; 984-93. doi: 10.1038/sj.cdd.4401924

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Gresko E, Roscic A, Ritterhoff S, Vichalkovski A, del Sal G, Schmitz ML

Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2.

EMBO J 2006; 1883-94. doi: 10.1038/sj.emboj.7601077

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Bergamaschi D, Samuels Y, Sullivan A, Zvelebil M, Breyssens H, Bisso A, Del Sal G, Syed N, Smith P, Gasco M, Crook T, Lu X

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

Nat Genet 2006; 1133-41. doi: 10.1038/ng1879

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Pinton P, Rimessi A, Marchi S, Orsini F, Migliaccio E, Giorgio M, Contursi C, Minucci S, Mantovani F, Wieckowski MR, Del Sal G, Pelicci PG, Rizzuto R

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc.

Science 2007; 659-63. doi: 10.1126/science.1135380

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Zita MM, Marchionni I, Bottos E, Righi M, Del Sal G, Cherubini E, Zacchi P

Post-phosphorylation prolyl isomerisation of gephyrin represents a mechanism to modulate glycine receptors function.

EMBO J 2007; 1761-71. doi: 10.1038/sj.emboj.7601625

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De Nicola F, Bruno T, Iezzi S, Di Padova M, Floridi A, Passananti C, Del Sal G, Fanciulli M

The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage.

J Biol Chem 2007; 19685-91. doi: 10.1074/jbc.M610282200

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Mantovani F, Tocco F, Girardini J, Smith P, Gasco M, Lu X, Crook T, Del Sal G

The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP.

Nat Struct Mol Biol 2007; 912-20. doi: 10.1038/nsmb1306

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Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di Iasio MG, Rustighi A, Del Sal G, Zauli G

Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells.

Blood 2008; 1287-94. doi: 10.1182/blood-2007-05-092031

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Faniello MC, Di Sanzo M, Quaresima B, Baudi F, Di Caro V, Cuda G, Morrone G, Del Sal G, Spinelli G, Venuta S, Costanzo F

p53-mediated downregulation of H ferritin promoter transcriptional efficiency via NF-Y.

Int J Biochem Cell Biol 2008; 2110-9. doi: 10.1016/j.biocel.2008.02.010

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Mauri F, McNamee LM, Lunardi A, Chiacchiera F, Del Sal G, Brodsky MH, Collavin L

Modification of Drosophila p53 by SUMO modulates its transactivation and pro-apoptotic functions.

J Biol Chem 2008; 20848-56. doi: 10.1074/jbc.M710186200

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Guida E, Bisso A, Fenollar-Ferrer C, Napoli M, Anselmi C, Girardini JE, Carloni P, Del Sal G

Peptide aptamers targeting mutant p53 induce apoptosis in tumor cells.

Cancer Res 2008; 6550-8. doi: 10.1158/0008-5472.CAN-08-0137

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Zucchelli S, Vilotti S, Calligaris R, Lavina ZS, Biagioli M, Foti R, De Maso L, Pinto M, Gorza M, Speretta E, Casseler C, Tell G, Del Sal G, Gustincich S

Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations.

Cell Death Differ 2009; 428-38. doi: 10.1038/cdd.2008.169

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Rustighi A, Tiberi L, Soldano A, Napoli M, Nuciforo P, Rosato A, Kaplan F, Capobianco A, Pece S, Di Fiore PP, Del Sal G

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer.

Nat Cell Biol 2009; 133-42. doi: 10.1038/ncb1822

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Gianni' M, Boldetti A, Guarnaccia V, Rambaldi A, Parrella E, Raska I, Rochette-Egly C, Del Sal G, Rustighi A, Terao M, Garattini E

Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARalpha and PML-RARalpha.

Cancer Res 2009; 1016-26. doi: 10.1158/0008-5472.CAN-08-2603

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Carnemolla A, Fossale E, Agostoni E, Michelazzi S, Calligaris R, De Maso L, Del Sal G, MacDonald ME, Persichetti F

Rrs1 is involved in endoplasmic reticulum stress response in Huntington disease.

J Biol Chem 2009; 18167-73. doi: 10.1074/jbc.M109.018325

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Lunardi A, Chiacchiera F, D'Este E, Carotti M, Dal Ferro M, Di Minin G, Del Sal G, Collavin L

The evolutionary conserved gene C16orf35 encodes a nucleo-cytoplasmic protein that interacts with p73.

Biochem Biophys Res Commun 2009; 428-33. doi: 10.1016/j.bbrc.2009.08.027

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Manganaro L, Lusic M, Gutierrez MI, Cereseto A, Del Sal G, Giacca M

Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes.

Nat Med 2010; 329-33. doi: 10.1038/nm.2102

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Drost J, Mantovani F, Tocco F, Elkon R, Comel A, Holstege H, Kerkhoven R, Jonkers J, Voorhoeve PM, Agami R, Del Sal G

BRD7 is a candidate tumour suppressor gene required for p53 function.

Nat Cell Biol 2010; 380-9. doi: 10.1038/ncb2038

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Lunardi A, Di Minin G, Provero P, Dal Ferro M, Carotti M, Del Sal G, Collavin L

A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network.

Proc Natl Acad Sci U S A 2010; 6322-7. doi: 10.1073/pnas.1002447107

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