Vacca D, Fiannaca A, Tramuto F, Cancila V, La Paglia L, Mazzucco W, Gulino A, La Rosa M, Maida CM, Morello G, Belmonte B, Casuccio A, Maugeri R, Iacopino G, Balistreri CR, Vitale F, Tripodo C, Urso A

Direct RNA Nanopore Sequencing of SARS-CoV-2 Extracted from Critical Material from Swabs.

Life (Basel) 2022; . doi: 10.3390/life12010069

Vernieri C, Fucà G, Ligorio F, Huber V, Vingiani A, Iannelli F, Raimondi A, Rinchai D, Frigè G, Belfiore A, Lalli L, Chiodoni C, Cancila V, Zanardi F, Ajazi A, Cortellino S, Vallacchi V, Squarcina P, Cova A, Pesce S, Frati P, Mall R, Corsetto PA, Rizzo AM, Ferraris C, Folli S, Garassino MC, Capri G, Bianchi G, Colombo MP, Minucci S, Foiani M, Longo VD, Apolone G, Torri V, Pruneri G, Bedognetti D, Rivoltini L, de Braud F

Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer.

Cancer Discov 2022; 90-107. doi: 10.1158/2159-8290.CD-21-0030

Granai M, Lazzi S, Mancini V, Akarca A, Santi R, Vergoni F, Sorrentino E, Guazzo R, Mundo L, Cevenini G, Tripodo C, Di Stefano G, Puccini B, Ponzoni M, Sabattini E, Agostinelli C, Bassüllü N, Tecimer T, Demiroz AS, Mnango L, Dirnhofer S, Quintanilla-Martinez L, Marafioti T, Fend F, Leoncini L

Burkitt lymphoma with a granulomatous reaction: an M1/Th1-polarised microenvironment is associated with controlled growth and spontaneous regression.

Histopathology 2022; 430-442. doi: 10.1111/his.14391

Simula L, Antonucci Y, Scarpelli G, Cancila V, Colamatteo A, Manni S, De Angelis B, Quintarelli C, Procaccini C, Matarese G, Tripodo C, Campello S

PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism.

Mol Oncol 2022; 188-205. doi: 10.1002/1878-0261.13103

Merlini A, Centomo ML, Ferrero G, Chiabotto G, Miglio U, Berrino E, Giordano G, Brusco S, Pisacane A, Maldi E, Sarotto I, Capozzi F, Lano C, Isella C, Crisafulli G, Aglietta M, Dei Tos AP, Sbaraglia M, Sangiolo D, D'Ambrosio L, Bardelli A, Pignochino Y, Grignani G

DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination.

Front Oncol 2022; 844250. doi: 10.3389/fonc.2022.844250

Stadiotti I, Santoro R, Scopece A, Pirola S, Guarino A, Polvani G, Maione AS, Ascione F, Li Q, Delia D, Foiani M, Pompilio G, Sommariva E

Pressure Overload Activates DNA-Damage Response in Cardiac Stromal Cells: A Novel Mechanism Behind Heart Failure With Preserved Ejection Fraction?

Front Cardiovasc Med 2022; 878268. doi: 10.3389/fcvm.2022.878268

Blasi F, Caiani EG, Cereda MG, Donetti D, Montorsi M, Panella V, Panina G, Pelagalli F, Speroni E

Six Drivers to Face the XXI Century Challenges and Build the New Healthcare System: "La Salute in Movimento" Manifesto.

Front Public Health 2022; 876625. doi: 10.3389/fpubh.2022.876625

Zattarin E, Nichetti F, Ligorio F, Mazzeo L, Lobefaro R, Fucà G, Peverelli G, Vingiani A, Bianchi GV, Capri G, de Braud F, Vernieri C

Case Report: Prolonged clinical benefit with sequential trastuzumab-containing treatments in a patient with advanced extramammary Paget disease of the groin.

Front Oncol 2022; 925551. doi: 10.3389/fonc.2022.925551

Di Cosimo S, La Rocca E, Ljevar S, De Santis MC, Bini M, Cappelletti V, Valenti M, Baili P, de Braud FG, Folli S, Scaperrotta G, Volpi C, Vingiani A, Vernieri C, Verderio P, Miceli R, Pruneri G

Moving HER2-low breast cancer predictive and prognostic data from clinical trials into the real world.

Front Mol Biosci 2022; 996434. doi: 10.3389/fmolb.2022.996434

Pusceddu S, Vernieri C, Di Maio M, Prinzi N, Torchio M, Corti F, Coppa J, Buzzoni R, Di Bartolomeo M, Milione M, Regnault B, Truong Thanh XM, Mazzaferro V, de Braud F

Impact of Diabetes and Metformin Use on Enteropancreatic Neuroendocrine Tumors: Post Hoc Analysis of the CLARINET Study.

Cancers (Basel) 2021; . doi: 10.3390/cancers14010069

Frayssinhes JA, Cerruti F, Laulin J, Cattaneo A, Bachi A, Apcher S, Coux O, Cascio P

PA28γ-20S proteasome is a proteolytic complex committed to degrade unfolded proteins.

Cell Mol Life Sci 2021; 45. doi: 10.1007/s00018-021-04045-9

Pignochino Y, Crisafulli G, Giordano G, Merlini A, Berrino E, Centomo ML, Chiabotto G, Brusco S, Basiricò M, Maldi E, Pisacane A, Leuci V, Sangiolo D, D'Ambrosio L, Aglietta M, Kasper B, Bardelli A, Grignani G

PARP1 Inhibitor and Trabectedin Combination Does Not Increase Tumor Mutational Burden in Advanced Sarcomas-A Preclinical and Translational Study.

Cancers (Basel) 2021; . doi: 10.3390/cancers13246295

Wan JCM, Mughal TI, Razavi P, Dawson SJ, Moss EL, Govindan R, Tan IB, Yap YS, Robinson WA, Morris CD, Besse B, Bardelli A, Tie J, Kopetz S, Rosenfeld N

Liquid biopsies for residual disease and recurrence.

Med 2021; 1292-1313. doi: 10.1016/j.medj.2021.11.001

Humphreys IR, Pei J, Baek M, Krishnakumar A, Anishchenko I, Ovchinnikov S, Zhang J, Ness TJ, Banjade S, Bagde SR, Stancheva VG, Li XH, Liu K, Zheng Z, Barrero DJ, Roy U, Kuper J, Fernández IS, Szakal B, Branzei D, Rizo J, Kisker C, Greene EC, Biggins S, Keeney S, Miller EA, Fromme JC, Hendrickson TL, Cong Q, Baker D

Computed structures of core eukaryotic protein complexes.

Science 2021; eabm4805. doi: 10.1126/science.abm4805

Wallis SS, Ventimiglia LN, Otigbah E, Infante E, Cuesta-Geijo MA, Kidiyoor GR, Carbajal MA, Fleck RA, Foiani M, Garcia-Manyes S, Martin-Serrano J, Agromayor M

The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair.

Dev Cell 2021; 3192-3202.e8. doi: 10.1016/j.devcel.2021.10.022

De Simone M, Chirichella M, Emming S, Mazzara S, Ranzani V, Gruarin P, Moschetti G, Pulvirenti N, Maglie S, Vasco C, Crosti MC, Rossetti G, Pagani M, Abrignani S, Monticelli S, Geginat J

Ex vivo microRNA and gene expression profiling of human Tr1-like cells suggests a role for miR-92a and -125a in the regulation of EOMES and IL-10R.

Eur J Immunol 2021; 3243-3246. doi: 10.1002/eji.202149315

Vounotrypidis E, Freissinger S, Cereda M, Monteduro D, Kortuem K, Priglinger S, Mayer B, Wolf A

Intravitreal injection associated rhegmatogenous retinal detachment: outcomes of a European analysis.

Graefes Arch Clin Exp Ophthalmol 2021; 3655-3664. doi: 10.1007/s00417-021-05261-6

Cereda MG, Parrulli S, Douven YGM, Faridpooya K, van Romunde S, Hüttmann G, Eixmann T, Schulz-Hildebrandt H, Kronreif G, Beelen M, de Smet MD

Clinical Evaluation of an Instrument-Integrated OCT-Based Distance Sensor for Robotic Vitreoretinal Surgery.

Ophthalmol Sci 2021; 100085. doi: 10.1016/j.xops.2021.100085

Jin Z, Dixon JG, Fiskum JM, Parekh HD, Sinicrope FA, Yothers G, Allegra CJ, Wolmark N, Haller D, Schmoll HJ, de Gramont A, Kerr R, Taieb J, Van Cutsem E, Tweleves C, O'Connell M, Saltz LB, Sadahiro S, Blanke CD, Tomita N, Seitz JF, Erlichman C, Yoshino T, Yamanaka T, Marsoni S, Andre T, Mahipal A, Goldberg RM, George TJ, Shi Q

Clinicopathological and Molecular Characteristics of Early-Onset Stage III Colon Adenocarcinoma: An Analysis of the ACCENT Database.

J Natl Cancer Inst 2021; 1693-1704. doi: 10.1093/jnci/djab123

Gandin A, Murugesan Y, Torresan V, Ulliana L, Citron A, Contessotto P, Battilana G, Panciera T, Ventre M, Netti AP, Nicola L, Piccolo S, Brusatin G

Simple yet effective methods to probe hydrogel stiffness for mechanobiology.

Sci Rep 2021; 22668. doi: 10.1038/s41598-021-01036-5

Sáinz-Jaspeado M, Smith RO, Plunde O, Pawelzik SC, Jin Y, Nordling S, Ding Y, Aspenström P, Hedlund M, Bastianello G, Ascione F, Li Q, Demir CS, Fernando D, Daniel G, Franco-Cereceda A, Kroon J, Foiani M, Petrova TV, Kilimann MW, Bäck M, Claesson-Welsh L

Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium.

Circulation 2021; 1629-1645. doi: 10.1161/CIRCULATIONAHA.121.054182

Pavani M, Bonaiuti P, Chiroli E, Gross F, Natali F, Macaluso F, Póti Á, Pasqualato S, Farkas Z, Pompei S, Cosentino Lagomarsino M, Rancati G, Szüts D, Ciliberto A

Epistasis, aneuploidy, and functional mutations underlie evolution of resistance to induced microtubule depolymerization.

EMBO J 2021; e108225. doi: 10.15252/embj.2021108225

Randon G, Yaeger R, Hechtman JF, Manca P, Fucà G, Walch H, Lee J, Élez E, Seligmann J, Mussolin B, Pagani F, Germani MM, Ambrosini M, Rossini D, Ratti M, Salvà F, Richman SD, Wood H, Nanjangud G, Gloghini A, Milione M, Bardelli A, de Braud F, Morano F, Cremolini C, Pietrantonio F

EGFR Amplification in Metastatic Colorectal Cancer.

J Natl Cancer Inst 2021; 1561-1569. doi: 10.1093/jnci/djab069

Sheldon H, Bridges E, Silva I, Masiero M, Favara DM, Wang D, Leek R, Snell C, Roxanis I, Kreuzer M, Gileadi U, Buffa FM, Banham A, Harris AL

ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression.

Mol Cancer Res 2021; 1957-1969. doi: 10.1158/1541-7786.MCR-21-0171

Invernizzi A, Parrulli S, Monteduro D, Cereda MG, Nguyen V, Staurenghi G, Cheung CMG, Gillies M, Teo KYC

Outer Retinal Layer Thickening Predicts the Onset of Exudative Neovascular Age-Related Macular Degeneration.

Am J Ophthalmol 2021; 19-27. doi: 10.1016/j.ajo.2021.05.015

Panebianco C, Pisati F, Ulaszewska M, Andolfo A, Villani A, Federici F, Laura M, Rizzi E, Potenza A, Latiano TP, Perri F, Tripodo C, Pazienza V

Tuning gut microbiota through a probiotic blend in gemcitabine-treated pancreatic cancer xenografted mice.

Clin Transl Med 2021; e580. doi: 10.1002/ctm2.580

Vorselen D, Barger SR, Wang Y, Cai W, Theriot JA, Gauthier NC, Krendel M

Phagocytic 'teeth' and myosin-II 'jaw' power target constriction during phagocytosis.

Elife 2021; . doi: 10.7554/eLife.68627

Monzo P, Crestani M, Chong YK, Ghisleni A, Hennig K, Li Q, Kakogiannos N, Giannotta M, Richichi C, Dini T, Dejana E, Maiuri P, Balland M, Sheetz MP, Pelicci G, Ang BT, Tang C, Gauthier NC

Adaptive mechanoproperties mediated by the formin FMN1 characterize glioblastoma fitness for invasion.

Dev Cell 2021; 2841-2855.e8. doi: 10.1016/j.devcel.2021.09.007

Bertolini G, Cancila V, Milione M, Lo Russo G, Fortunato O, Zaffaroni N, Tortoreto M, Centonze G, Chiodoni C, Facchinetti F, Pollaci G, Taiè G, Giovinazzo F, Moro M, Camisaschi C, De Toma A, D'Alterio C, Pastorino U, Tripodo C, Scala S, Sozzi G, Roz L

A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer.

Mol Ther 2021; 2963-2978. doi: 10.1016/j.ymthe.2021.05.014

Van Beek JJP, Puccio S, Roberto A, De Paoli F, Graziano G, Salviato E, Alvisi G, Zanon V, Scarpa A, Zaghi E, Calvi M, Di Vito C, Mineri R, Sarina B, De Philippis C, Santoro A, Mariotti J, Bramanti S, Ferrari F, Castagna L, Mavilio D, Lugli E

Single-cell profiling reveals the dynamics of cytomegalovirus-specific T cells in haploidentical hematopoietic stem cell transplantation.

Haematologica 2021; 2768-2773. doi: 10.3324/haematol.2020.276352

Moreno-Layseca P, Jäntti NZ, Godbole R, Sommer C, Jacquemet G, Al-Akhrass H, Conway JRW, Kronqvist P, Kallionpää RE, Oliveira-Ferrer L, Cervero P, Linder S, Aepfelbacher M, Zauber H, Rae J, Parton RG, Disanza A, Scita G, Mayor S, Selbach M, Veltel S, Ivaska J

Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.

Nat Cell Biol 2021; 1073-1084. doi: 10.1038/s41556-021-00767-x

Bampton A, Gatt A, Humphrey J, Cappelli S, Bhattacharya D, Foti S, Brown AL, Asi Y, Low YH, Foiani M, Raj T, Buratti E, Fratta P, Lashley T

HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing.

Acta Neuropathol 2021; 609-627. doi: 10.1007/s00401-021-02340-0

Nader GPF, Agüera-Gonzalez S, Routet F, Gratia M, Maurin M, Cancila V, Cadart C, Palamidessi A, Ramos RN, San Roman M, Gentili M, Yamada A, Williart A, Lodillinsky C, Lagoutte E, Villard C, Viovy JL, Tripodo C, Galon J, Scita G, Manel N, Chavrier P, Piel M

Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion.

Cell 2021; 5230-5246.e22. doi: 10.1016/j.cell.2021.08.035

Ajazi A, Bruhn C, Shubassi G, Lucca C, Ferrari E, Cattaneo A, Bachi A, Manfrini N, Biffo S, Martini E, Minucci S, Vernieri C, Foiani M

Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis.

Dev Cell 2021; 2607-2622.e6. doi: 10.1016/j.devcel.2021.08.019

%PLACEHOLDER%