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Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia.

Cancer Res 2004; 8816-20. doi: 10.1158/0008-5472.CAN-04-1923

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Buffa FM, Verhaegen F

Backscatter and dose perturbations for low- to medium-energy electron point sources at the interface between materials with different atomic numbers.

Radiat Res 2004; 693-701. doi: 10.1667/rr3271

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Disanza A, Carlier MF, Stradal TE, Didry D, Frittoli E, Confalonieri S, Croce A, Wehland J, Di Fiore PP, Scita G

Eps8 controls actin-based motility by capping the barbed ends of actin filaments.

Nat Cell Biol 2004; 1180-8. doi: 10.1038/ncb1199

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Croce A, Cassata G, Disanza A, Gagliani MC, Tacchetti C, Malabarba MG, Carlier MF, Scita G, Baumeister R, Di Fiore PP

A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans.

Nat Cell Biol 2004; 1173-9. doi: 10.1038/ncb1198

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Kohli M, Yu J, Seaman C, Bardelli A, Kinzler KW, Vogelstein B, Lengauer C, Zhang L

SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells.

Proc Natl Acad Sci U S A 2004; 16897-902. doi: 10.1073/pnas.0403405101

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Gostissa M, Morelli M, Mantovani F, Guida E, Piazza S, Collavin L, Brancolini C, Schneider C, Del Sal G

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

J Biol Chem 2004; 48013-23. doi: 10.1074/jbc.M310801200

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Parker BS, Argani P, Cook BP, Liangfeng H, Chartrand SD, Zhang M, Saha S, Bardelli A, Jiang Y, St Martin TB, Nacht M, Teicher BA, Klinger KW, Sukumar S, Madden SL

Alterations in vascular gene expression in invasive breast carcinoma.

Cancer Res 2004; 7857-66. doi: 10.1158/0008-5472.CAN-04-1976

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Branzei D, Seki M, Enomoto T

Rad18/Rad5/Mms2-mediated polyubiquitination of PCNA is implicated in replication completion during replication stress.

Genes Cells 2004; 1031-42. doi: 10.1111/j.1365-2443.2004.00787.x

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Iannitto E, Ambrosetti A, Ammatuna E, Colosio M, Florena AM, Tripodo C, Minardi V, Calvaruso G, Mitra ME, Pizzolo G, Menestrina F, Franco V

Splenic marginal zone lymphoma with or without villous lymphocytes. Hematologic findings and outcomes in a series of 57 patients.

Cancer 2004; 2050-7. doi: 10.1002/cncr.20596

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Ira G, Pellicioli A, Balijja A, Wang X, Fiorani S, Carotenuto W, Liberi G, Bressan D, Wan L, Hollingsworth NM, Haber JE, Foiani M

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1.

Nature 2004; 1011-7. doi: 10.1038/nature02964

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Sager JA, Benvenuti S, Bardelli A

PRL-3: a phosphatase for metastasis?

Cancer Biol Ther 2004; 952-3. doi: 10.4161/cbt.3.10.1115

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Dupont S, Zacchigna L, Adorno M, Soligo S, Volpin D, Piccolo S, Cordenonsi M

Convergence of p53 and TGF-beta signaling networks.

Cancer Lett 2004; 129-38. doi: 10.1016/j.canlet.2004.06.008

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Jolliffe NA, Brown JC, Neumann U, Vicré M, Bachi A, Hawes C, Ceriotti A, Roberts LM, Frigerio L

Transport of ricin and 2S albumin precursors to the storage vacuoles of Ricinus communis endosperm involves the Golgi and VSR-like receptors.

Plant J 2004; 821-33. doi: 10.1111/j.1365-313X.2004.02167.x

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Eriksen JG, Buffa FM, Alsner J, Steiniche T, Bentzen SM, Overgaard J

Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas.

Radiother Oncol 2004; 275-82. doi: 10.1016/j.radonc.2004.07.014

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Franco V, Tripodo C, Rizzo A, Stella M, Florena AM

Bone marrow biopsy in Hodgkin's lymphoma.

Eur J Haematol 2004; 149-55. doi: 10.1111/j.1600-0609.2004.00292.x

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Sasaki Y, Casola S, Kutok JL, Rajewsky K, Schmidt-Supprian M

TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

J Immunol 2004; 2245-52. doi: 10.4049/jimmunol.173.4.2245

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Masciadri B, Areces LB, Carpinelli P, Foiani M, Draetta G, Fiore F

Characterization of the BUD31 gene of Saccharomyces cerevisiae.

Biochem Biophys Res Commun 2004; 1342-50. doi: 10.1016/j.bbrc.2004.05.228

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Liebner S, Cattelino A, Gallini R, Rudini N, Iurlaro M, Piccolo S, Dejana E

Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse.

J Cell Biol 2004; 359-67. doi: 10.1083/jcb.200403050

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d'Adda di Fagagna F, Teo SH, Jackson SP

Functional links between telomeres and proteins of the DNA-damage response.

Genes Dev 2004; 1781-99. doi: 10.1101/gad.1214504

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Schmidt-Supprian M, Tian J, Ji H, Terhorst C, Bhan AK, Grant EP, Pasparakis M, Casola S, Coyle AJ, Rajewsky K

I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion.

J Immunol 2004; 1612-9. doi: 10.4049/jimmunol.173.3.1612

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Florena AM, Tripodo C, Iannitto E, Porcasi R, Ingrao S, Franco V

Value of bone marrow biopsy in the diagnosis of essential thrombocythemia.

Haematologica 2004; 911-9.

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O'Brien WT, Harper AD, Jové F, Woodgett JR, Maretto S, Piccolo S, Klein PS

Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium.

J Neurosci 2004; 6791-8. doi: 10.1523/JNEUROSCI.4753-03.2004

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Conti A, Sanchez-Ruiz Y, Bachi A, Beretta L, Grandi E, Beltramo M, Alessio M

Proteome study of human cerebrospinal fluid following traumatic brain injury indicates fibrin(ogen) degradation products as trauma-associated markers.

J Neurotrauma 2004; 854-63. doi: 10.1089/0897715041526212

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Mantovani F, Gostissa M, Collavin L, Del Sal G

KeePin' the p53 family in good shape.

Cell Cycle 2004; 905-11.

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Shechter D, Costanzo V, Gautier J

ATR and ATM regulate the timing of DNA replication origin firing.

Nat Cell Biol 2004; 648-55. doi: 10.1038/ncb1145

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Collavin L, Gostissa M, Avolio F, Secco P, Ronchi A, Santoro C, Del Sal G

Modification of the erythroid transcription factor GATA-1 by SUMO-1.

Proc Natl Acad Sci U S A 2004; 8870-5. doi: 10.1073/pnas.0308605101

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Carro S, Bergo A, Mengoni M, Bachi A, Badaracco G, Kilstrup-Nielsen C, Landsberger N

A novel protein, Xenopus p20, influences the stability of MeCP2 through direct interaction.

J Biol Chem 2004; 25623-31. doi: 10.1074/jbc.M402571200

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Mantovani F, Piazza S, Gostissa M, Strano S, Zacchi P, Mantovani R, Blandino G, Del Sal G

Pin1 links the activities of c-Abl and p300 in regulating p73 function.

Mol Cell 2004; 625-36. doi: 10.1016/j.molcel.2004.05.007

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Buffa FM, Bentzen SM, Daley FM, Dische S, Saunders MI, Richman PI, Wilson GD

Molecular marker profiles predict locoregional control of head and neck squamous cell carcinoma in a randomized trial of continuous hyperfractionated accelerated radiotherapy.

Clin Cancer Res 2004; 3745-54. doi: 10.1158/1078-0432.CCR-03-0248

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Paroni G, Mizzau M, Henderson C, Del Sal G, Schneider C, Brancolini C

Caspase-dependent regulation of histone deacetylase 4 nuclear-cytoplasmic shuttling promotes apoptosis.

Mol Biol Cell 2004; 2804-18. doi: 10.1091/mbc.e03-08-0624

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Stradal TE, Rottner K, Disanza A, Confalonieri S, Innocenti M, Scita G

Regulation of actin dynamics by WASP and WAVE family proteins.

Trends Cell Biol 2004; 303-11. doi: 10.1016/j.tcb.2004.04.007

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Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE

Mutational analysis of the tyrosine phosphatome in colorectal cancers.

Science 2004; 1164-6. doi: 10.1126/science.1096096

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Lanzetti L, Palamidessi A, Areces L, Scita G, Di Fiore PP

Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.

Nature 2004; 309-14. doi: 10.1038/nature02542

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Labianca R, Fossati R, Zaniboni A, Torri V, Marsoni S, Nitti D, Boffi L, Scatizzi M, Tardio B, Mastrodonato N, Banducci S, Consani G, Pancera G

Randomized trial of intraportal and/or systemic adjuvant chemotherapy in patients with colon carcinoma.

J Natl Cancer Inst 2004; 750-8. doi: 10.1093/jnci/djh132

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Saverino D, Ghiotto F, Merlo A, Bruno S, Battini L, Occhino M, Maffei M, Tenca C, Pileri S, Baldi L, Fabbi M, Bachi A, De Santanna A, Grossi CE, Ciccone E

Specific recognition of the viral protein UL18 by CD85j/LIR-1/ILT2 on CD8+ T cells mediates the non-MHC-restricted lysis of human cytomegalovirus-infected cells.

J Immunol 2004; 5629-37. doi: 10.4049/jimmunol.172.9.5629

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Costanzo V, Paull T, Gottesman M, Gautier J

Mre11 assembles linear DNA fragments into DNA damage signaling complexes.

PLoS Biol 2004; E110. doi: 10.1371/journal.pbio.0020110

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Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, Yan H, Gazdar A, Powell SM, Riggins GJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE

High frequency of mutations of the PIK3CA gene in human cancers.

Science 2004; 554. doi: 10.1126/science.1096502

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Innocenti M, Zucconi A, Disanza A, Frittoli E, Areces LB, Steffen A, Stradal TE, Di Fiore PP, Carlier MF, Scita G

Abi1 is essential for the formation and activation of a WAVE2 signalling complex.

Nat Cell Biol 2004; 319-27. doi: 10.1038/ncb1105

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Polo S, Pece S, Di Fiore PP

Endocytosis and cancer.

Curr Opin Cell Biol 2004; 156-61. doi: 10.1016/j.ceb.2004.02.003

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