Galietta A, Gunby RH, Redaelli S, Stano P, Carniti C, Bachi A, Tucker PW, Tartari CJ, Huang CJ, Colombo E, Pulford K, Puttini M, Piazza RG, Ruchatz H, Villa A, Donella-Deana A, Marin O, Perrotti D, Gambacorti-Passerini C

NPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphoma.

Blood 2007; 2600-9. doi: 10.1182/blood-2006-01-028647

Leggi ora

Nuciforo PG, Luise C, Capra M, Pelosi G, d'Adda di Fagagna F

Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression.

Carcinogenesis 2007; 2082-8. doi: 10.1093/carcin/bgm108

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Mantovani F, Tocco F, Girardini J, Smith P, Gasco M, Lu X, Crook T, Del Sal G

The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP.

Nat Struct Mol Biol 2007; 912-20. doi: 10.1038/nsmb1306

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Bosse T, Ehinger J, Czuchra A, Benesch S, Steffen A, Wu X, Schloen K, Niemann HH, Scita G, Stradal TE, Brakebusch C, Rottner K

Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.

Mol Cell Biol 2007; 6615-28. doi: 10.1128/MCB.00367-07

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Errico A, Costanzo V, Hunt T

Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts.

Proc Natl Acad Sci U S A 2007; 14929-34. doi: 10.1073/pnas.0706347104

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Arena S, Isella C, Martini M, de Marco A, Medico E, Bardelli A

Knock-in of oncogenic Kras does not transform mouse somatic cells but triggers a transcriptional response that classifies human cancers.

Cancer Res 2007; 8468-76. doi: 10.1158/0008-5472.CAN-07-1126

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Martello G, Zacchigna L, Inui M, Montagner M, Adorno M, Mamidi A, Morsut L, Soligo S, Tran U, Dupont S, Cordenonsi M, Wessely O, Piccolo S

MicroRNA control of Nodal signalling.

Nature 2007; 183-8. doi: 10.1038/nature06100

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Zaghetto AA, Paina S, Mantero S, Platonova N, Peretto P, Bovetti S, Puche A, Piccolo S, Merlo GR

Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.

J Neurosci 2007; 9757-68. doi: 10.1523/JNEUROSCI.0763-07.2007

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Muzio M, Scielzo C, Frenquelli M, Bachi A, De Palma M, Alessio M, Ghia P, Caligaris-Cappio F

HS1 complexes with cytoskeleton adapters in normal and malignant chronic lymphocytic leukemia B cells.

Leukemia 2007; 2067-70. doi: 10.1038/sj.leu.2404744

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Campisi J, d'Adda di Fagagna F

Cellular senescence: when bad things happen to good cells.

Nat Rev Mol Cell Biol 2007; 729-40. doi: 10.1038/nrm2233

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Sessa C, Perotti A, Lladò A, Cresta S, Capri G, Voi M, Marsoni S, Corradino I, Gianni L

Phase I clinical study of the novel epothilone B analogue BMS-310705 given on a weekly schedule.

Ann Oncol 2007; 1548-53. doi: 10.1093/annonc/mdm198

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Giannola LI, De Caro V, Giandalia G, Siragusa MG, Tripodo C, Florena AM, Campisi G

Release of naltrexone on buccal mucosa: permeation studies, histological aspects and matrix system design.

Eur J Pharm Biopharm 2007; 425-33. doi: 10.1016/j.ejpb.2007.02.020

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Ferrari F, Bortoluzzi S, Coppe A, Basso D, Bicciato S, Zini R, Gemelli C, Danieli GA, Ferrari S

Genomic expression during human myelopoiesis.

BMC Genomics 2007; 264. doi: 10.1186/1471-2164-8-264

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Saletta F, Matullo G, Manuguerra M, Arena S, Bardelli A, Vineis P

Exposure to the tobacco smoke constituent 4-aminobiphenyl induces chromosomal instability in human cancer cells.

Cancer Res 2007; 7088-94. doi: 10.1158/0008-5472.CAN-06-4420

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Piccoli G, Verpelli C, Tonna N, Romorini S, Alessio M, Nairn AC, Bachi A, Sala C

Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons.

J Proteome Res 2007; 3203-15. doi: 10.1021/pr0701308

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Díaz VM, Bachi A, Blasi F

Purification of the Prep1 interactome identifies novel pathways regulated by Prep1.

Proteomics 2007; 2617-23. doi: 10.1002/pmic.200700197

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Camerini S, Polci ML, Restuccia U, Usuelli V, Malgaroli A, Bachi A

A novel approach to identify proteins modified by nitric oxide: the HIS-TAG switch method.

J Proteome Res 2007; 3224-31. doi: 10.1021/pr0701456

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Short SC, Buffa FM, Bourne S, Koritzinsky M, Wouters BG, Bentzen SM

Dose- and time-dependent changes in gene expression in human glioma cells after low radiation doses.

Radiat Res 2007; 199-208. doi: 10.1667/RR0940.1

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Bermejo R, Doksani Y, Capra T, Katou YM, Tanaka H, Shirahige K, Foiani M

Top1- and Top2-mediated topological transitions at replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation.

Genes Dev 2007; 1921-36. doi: 10.1101/gad.432107

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Chalmers AJ, Bentzen SM, Buffa FM

A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose.

Theor Biol Med Model 2007; 25. doi: 10.1186/1742-4682-4-25

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De Nicola F, Bruno T, Iezzi S, Di Padova M, Floridi A, Passananti C, Del Sal G, Fanciulli M

The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage.

J Biol Chem 2007; 19685-91. doi: 10.1074/jbc.M610282200

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Arena S, Pisacane A, Mazzone M, Comoglio PM, Bardelli A

Genetic targeting of the kinase activity of the Met receptor in cancer cells.

Proc Natl Acad Sci U S A 2007; 11412-7. doi: 10.1073/pnas.0703205104

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Branzei D, Foiani M

Interplay of replication checkpoints and repair proteins at stalled replication forks.

DNA Repair (Amst) 2007; 994-1003. doi: 10.1016/j.dnarep.2007.02.018

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Onofri F, Messa M, Matafora V, Bonanno G, Corradi A, Bachi A, Valtorta F, Benfenati F

Synapsin phosphorylation by SRC tyrosine kinase enhances SRC activity in synaptic vesicles.

J Biol Chem 2007; 15754-67. doi: 10.1074/jbc.M701051200

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Bassetti F, Lagomarsino MC, Bassetti B, Jona P

Random networks tossing biased coins.

Phys Rev E Stat Nonlin Soft Matter Phys 2007; 056109. doi: 10.1103/PhysRevE.75.056109

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Li B, Rhéaume C, Teng A, Bilanchone V, Munguia JE, Hu M, Jessen S, Piccolo S, Waterman ML, Dai X

Developmental phenotypes and reduced Wnt signaling in mice deficient for pygopus 2.

Genesis 2007; 318-25. doi: 10.1002/dvg.20299

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Thai TH, Calado DP, Casola S, Ansel KM, Xiao C, Xue Y, Murphy A, Frendewey D, Valenzuela D, Kutok JL, Schmidt-Supprian M, Rajewsky N, Yancopoulos G, Rao A, Rajewsky K

Regulation of the germinal center response by microRNA-155.

Science 2007; 604-8. doi: 10.1126/science.1141229

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Gauthier NC, Monzo P, Gonzalez T, Doye A, Oldani A, Gounon P, Ricci V, Cormont M, Boquet P

Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin.

J Cell Biol 2007; 343-54. doi: 10.1083/jcb.200609061

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Balakrishnan A, Bleeker FE, Lamba S, Rodolfo M, Daniotti M, Scarpa A, van Tilborg AA, Leenstra S, Zanon C, Bardelli A

Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma.

Cancer Res 2007; 3545-50. doi: 10.1158/0008-5472.CAN-07-0065

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Zita MM, Marchionni I, Bottos E, Righi M, Del Sal G, Cherubini E, Zacchi P

Post-phosphorylation prolyl isomerisation of gephyrin represents a mechanism to modulate glycine receptors function.

EMBO J 2007; 1761-71. doi: 10.1038/sj.emboj.7601625

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Winter SC, Buffa FM, Silva P, Miller C, Valentine HR, Turley H, Shah KA, Cox GJ, Corbridge RJ, Homer JJ, Musgrove B, Slevin N, Sloan P, Price P, West CM, Harris AL

Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers.

Cancer Res 2007; 3441-9. doi: 10.1158/0008-5472.CAN-06-3322

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Casola S

Control of peripheral B-cell development.

Curr Opin Immunol 2007; 143-9. doi: 10.1016/j.coi.2007.02.010

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Cosentino Lagomarsino M, Jona P, Bassetti B, Isambert H

Hierarchy and feedback in the evolution of the Escherichia coli transcription network.

Proc Natl Acad Sci U S A 2007; 5516-20. doi: 10.1073/pnas.0609023104

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Ciliberto A, Capuani F, Tyson JJ

Modeling networks of coupled enzymatic reactions using the total quasi-steady state approximation.

PLoS Comput Biol 2007; e45. doi: 10.1371/journal.pcbi.0030045

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Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, Zanon C, Moroni M, Veronese S, Siena S, Bardelli A

Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

Cancer Res 2007; 2643-8. doi: 10.1158/0008-5472.CAN-06-4158

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Woelk T, Sigismund S, Penengo L, Polo S

The ubiquitination code: a signalling problem.

Cell Div 2007; 11. doi: 10.1186/1747-1028-2-11

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Sessa C, Cresta S, Cerny T, Baselga J, Rota Caremoli E, Malossi A, Hess D, Trigo J, Zucchetti M, D'Incalci M, Zaniboni A, Capri G, Gatti B, Carminati P, Zanna C, Marsoni S, Gianni L

Concerted escalation of dose and dosing duration in a phase I study of the oral camptothecin gimatecan (ST1481) in patients with advanced solid tumors.

Ann Oncol 2007; 561-8. doi: 10.1093/annonc/mdl418

Leggi ora

Tripodo C, Porcasi R, Guarnotta C, Ingrao S, Campisi V, Florena AM, Franco V

C1q production by bone marrow stromal cells.

Scand J Immunol 2007; 308-9. doi: 10.1111/j.1365-3083.2006.01871.x

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D'Angiolella V, Palazzo L, Santarpia C, Costanzo V, Grieco D

Role for non-proteolytic control of M-phase-promoting factor activity at M-phase exit.

PLoS One 2007; e247. doi: 10.1371/journal.pone.0000247

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Cordenonsi M, Montagner M, Adorno M, Zacchigna L, Martello G, Mamidi A, Soligo S, Dupont S, Piccolo S

Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.

Science 2007; 840-3. doi: 10.1126/science.1135961

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Pinton P, Rimessi A, Marchi S, Orsini F, Migliaccio E, Giorgio M, Contursi C, Minucci S, Mantovani F, Wieckowski MR, Del Sal G, Pelicci PG, Rizzuto R

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc.

Science 2007; 659-63. doi: 10.1126/science.1135380

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Cosentino Lagomarsino M, Tanase C, Vos JW, Emons AM, Mulder BM, Dogterom M

Microtubule organization in three-dimensional confined geometries: evaluating the role of elasticity through a combined in vitro and modeling approach.

Biophys J 2007; 1046-57. doi: 10.1529/biophysj.105.076893

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Francia S, Weiss RS, d'Adda di Fagagna F

Need telomere maintenance? Call 911.

Cell Div 2007; 3. doi: 10.1186/1747-1028-2-3

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Magnoni C, Tenedini E, Ferrari F, Benassi L, Bernardi C, Gualdi G, Bertazzoni G, Roncaglia E, Fantoni L, Manfredini R, Bicciato S, Ferrari S, Giannetti A, Tagliafico E

Transcriptional profiles in melanocytes from clinically unaffected skin distinguish the neoplastic growth pattern in patients with melanoma.

Br J Dermatol 2007; 62-71. doi: 10.1111/j.1365-2133.2006.07564.x

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Tripodo C, Florena AM, Porcasi R, Ingrao S, Guarnotta C, Franco V

Constant detection of cyclooxygenase 2 in terminal stages of myeloid maturation.

Acta Haematol 2007; 48-50. doi: 10.1159/000096788

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Florena AM, Tripodo C, Guarnotta C, Ingrao S, Porcasi R, Martorana A, Lo Bosco G, Cabibi D, Franco V

Associations between Notch-2, Akt-1 and HER2/neu expression in invasive human breast cancer: a tissue microarray immunophenotypic analysis on 98 patients.

Pathobiology 2007; 317-22. doi: 10.1159/000110024

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