Hashimoto Y, Ray Chaudhuri A, Lopes M, Costanzo V

Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis.

Nat Struct Mol Biol 2010; 1305-11. doi: 10.1038/nsmb.1927

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Piergiovanni G, Costanzo V

GEMC1 is a novel TopBP1-interacting protein involved in chromosomal DNA replication.

Cell Cycle 2010; 3662-6. doi: 10.4161/cc.9.18.13060

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Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication.

Nat Cell Biol 2010; 484-91. doi: 10.1038/ncb2050

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Errico A, Costanzo V

Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns.

EMBO Rep 2010; 270-8. doi: 10.1038/embor.2010.27

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Errico A, Cosentino C, Rivera T, Losada A, Schwob E, Hunt T, Costanzo V

Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion.

EMBO J 2009; 3681-92. doi: 10.1038/emboj.2009.304

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Garner E, Costanzo V

Studying the DNA damage response using in vitro model systems.

DNA Repair (Amst) 2009; 1025-37. doi: 10.1016/j.dnarep.2009.04.015

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Costanzo V, Chaudhuri J, Fung JC, Moran JV

Dealing with dangerous accidents: DNA double-strand breaks take centre stage. Symposium on Genome Instability and DNA Repair.

EMBO Rep 2009; 837-42. doi: 10.1038/embor.2009.173

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Smith E, Costanzo V

Responding to chromosomal breakage during M-phase: insights from a cell-free system.

Cell Div 2009; 15. doi: 10.1186/1747-1028-4-15

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Brown N, Costanzo V

An ATM and ATR dependent pathway targeting centrosome dependent spindle assembly.

Cell Cycle 2009; 1997-2001. doi: 10.4161/cc.8.13.8987

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Smith E, Dejsuphong D, Balestrini A, Hampel M, Lenz C, Takeda S, Vindigni A, Costanzo V

An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63.

Nat Cell Biol 2009; 278-85. doi: 10.1038/ncb1835

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Takaki T, Trenz K, Costanzo V, Petronczki M

Polo-like kinase 1 reaches beyond mitosis--cytokinesis, DNA damage response, and development.

Curr Opin Cell Biol 2008; 650-60. doi: 10.1016/j.ceb.2008.10.005

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Jazayeri A, Balestrini A, Garner E, Haber JE, Costanzo V

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.

EMBO J 2008; 1953-62. doi: 10.1038/emboj.2008.128

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Trenz K, Errico A, Costanzo V

Plx1 is required for chromosomal DNA replication under stressful conditions.

EMBO J 2008; 876-85. doi: 10.1038/emboj.2008.29

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Errico A, Costanzo V, Hunt T

Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts.

Proc Natl Acad Sci U S A 2007; 14929-34. doi: 10.1073/pnas.0706347104

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D'Angiolella V, Palazzo L, Santarpia C, Costanzo V, Grieco D

Role for non-proteolytic control of M-phase-promoting factor activity at M-phase exit.

PLoS One 2007; e247. doi: 10.1371/journal.pone.0000247

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Trenz K, Smith E, Smith S, Costanzo V

ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks.

EMBO J 2006; 1764-74. doi: 10.1038/sj.emboj.7601045

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Sobeck A, Stone S, Costanzo V, de Graaf B, Reuter T, de Winter J, Wallisch M, Akkari Y, Olson S, Wang W, Joenje H, Christian JL, Lupardus PJ, Cimprich KA, Gautier J, Hoatlin ME

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks.

Mol Cell Biol 2006; 425-37. doi: 10.1128/MCB.26.2.425-437.2006

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Shechter D, Costanzo V, Gautier J

ATR and ATM regulate the timing of DNA replication origin firing.

Nat Cell Biol 2004; 648-55. doi: 10.1038/ncb1145

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Costanzo V, Paull T, Gottesman M, Gautier J

Mre11 assembles linear DNA fragments into DNA damage signaling complexes.

PLoS Biol 2004; E110. doi: 10.1371/journal.pbio.0020110

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Costanzo V, Gautier J

Xenopus cell-free extracts to study DNA damage checkpoints.

Methods Mol Biol 2004; 255-67. doi: 10.1385/1-59259-646-0:255

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Costanzo V, Robertson K, Gautier J

Xenopus cell-free extracts to study the DNA damage response.

Methods Mol Biol 2004; 213-27. doi: 10.1385/1-59259-788-2:213

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Shechter D, Costanzo V, Gautier J

Regulation of DNA replication by ATR: signaling in response to DNA intermediates.

DNA Repair (Amst) 2004; 901-8. doi: 10.1016/j.dnarep.2004.03.020

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Costanzo V, Shechter D, Lupardus PJ, Cimprich KA, Gottesman M, Gautier J

An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication.

Mol Cell 2003; 203-13. doi: 10.1016/s1097-2765(02)00799-2

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Costanzo V, Gautier J

Single-strand DNA gaps trigger an ATR- and Cdc7-dependent checkpoint.

Cell Cycle 2003; 17. doi: 10.4161/cc.2.1.290

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Vitolo OV, Sant'Angelo A, Costanzo V, Battaglia F, Arancio O, Shelanski M

Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling.

Proc Natl Acad Sci U S A 2002; 13217-21. doi: 10.1073/pnas.172504199

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D'Angiolella V, Costanzo V, Gottesman ME, Avvedimento EV, Gautier J, Grieco D

Role for cyclin-dependent kinase 2 in mitosis exit.

Curr Biol 2001; 1221-6. doi: 10.1016/s0960-9822(01)00352-9

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Costanzo V, Robertson K, Bibikova M, Kim E, Grieco D, Gottesman M, Carroll D, Gautier J

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

Mol Cell 2001; 137-47. doi: 10.1016/s1097-2765(01)00294-5

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Greenwood J, Costanzo V, Robertson K, Hensey C, Gautier J

Responses to DNA damage in Xenopus: cell death or cell cycle arrest.

Novartis Found Symp 2001; 221-30; discussion 230-4. doi: 10.1002/0470846666.ch17

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Costanzo V, Robertson K, Ying CY, Kim E, Avvedimento E, Gottesman M, Grieco D, Gautier J

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage.

Mol Cell 2000; 649-59. doi: 10.1016/s1097-2765(00)00063-0

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Costanzo V, Avvedimento EV, Gottesman ME, Gautier J, Grieco D

Protein kinase A is required for chromosomal DNA replication.

Curr Biol 1999; 903-6. doi: 10.1016/s0960-9822(99)80395-9

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